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Add gene selector for custom genes
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parent
780e608ee1
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8 changed files with 168 additions and 36 deletions
99
R/gene_selector.R
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99
R/gene_selector.R
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#' Create the UI for a gene selector.
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#'
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#' @param id ID for namespacing.
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#'
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#' @return The user interface
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#' @noRd
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gene_selector_ui <- function(id) {
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named_genes <- ubigen::genes[hgnc_name != ""]
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named_genes <- unique(named_genes, by = "hgnc_name")
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gene_choices <- named_genes$gene
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names(gene_choices) <- named_genes$hgnc_name
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verticalLayout(
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selectInput(
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NS(id, "identifier_type"),
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verticalLayout(
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strong("Gene identifiers"),
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paste0(
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"Select whether you want to pick or enter custom genes to assess ",
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"how ubiquitous they are."
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)
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),
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choices = list(
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"Select from list" = "list",
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"Enter HGNC symbols" = "hgnc",
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"Enter Ensembl gene IDs" = "ensembl"
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)
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),
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tabsetPanel(
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id = NS(id, "custom_input"),
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type = "hidden",
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tabPanelBody(
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"list",
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shinyvs::virtualSelectInput(
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NS(id, "selected_genes"),
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label = NULL,
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choices = gene_choices,
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multiple = TRUE,
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search = TRUE,
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selectAllOnlyVisible = TRUE
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),
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),
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tabPanelBody(
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"hgnc",
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textAreaInput(
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NS(id, "hgnc_names_raw"),
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label = NULL,
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height = "250px"
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)
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),
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tabPanelBody(
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"ensembl",
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textAreaInput(
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NS(id, "gene_ids_raw"),
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label = NULL,
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height = "250px"
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)
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)
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)
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)
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}
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#' Application logic for the gene selector.
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#'
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#' @param id ID for namespacing.
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#'
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#' @return A reactive containing the selected gene IDs.
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#' @noRd
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gene_selector_server <- function(id) {
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moduleServer(id, function(input, output, session) {
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observe({
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updateTabsetPanel(
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session,
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"custom_input",
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selected = input$identifier_type
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)
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})
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reactive({
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gene_ids <- if (input$identifier_type == "list") {
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input$selected_genes
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} else if (input$identifier_type == "hgnc") {
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inputs <- unique(strsplit(input$hgnc_names_raw, "\\s+")[[1]])
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inputs <- inputs[inputs != ""]
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ubigen::genes[hgnc_name %chin% inputs, gene]
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} else {
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inputs <- unique(strsplit(input$gene_ids_raw, "\\s+")[[1]])
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inputs <- inputs[inputs != ""]
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ubigen::genes[gene %chin% inputs, gene]
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}
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if (length(gene_ids > 100)) {
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gene_ids[seq_len(100)]
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} else {
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gene_ids
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}
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})
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})
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}
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