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| Package: ubigen | ||||
| Title: Graphical Interface for Finding Patterns in Gene Expression | ||||
| Version: 0.0.0.9000 | ||||
| Authors@R: | ||||
|     person( | ||||
|         "Elias", | ||||
|         "Projahn", | ||||
|         email = "elias@johrpan.de", | ||||
|         role = c("aut", "cre"), | ||||
|         comment = c(ORCID = "0000-0002-4153-4071") | ||||
|     ) | ||||
| Description: This package contains precomputed data including comparisons in | ||||
|     gene expression. It provides a graphical interface to analyze and visualize | ||||
|     those data. | ||||
| License: AGPL (>= 3) | ||||
| Encoding: UTF-8 | ||||
| Roxygen: list(markdown = TRUE) | ||||
| RoxygenNote: 7.1.2 | ||||
| Depends: | ||||
|     R (>= 2.10) | ||||
| LazyData: true | ||||
| Imports: | ||||
|     bslib, | ||||
|     data.table, | ||||
|     DT, | ||||
|     glue, | ||||
|     shiny | ||||
							
								
								
									
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| GNU Affero General Public License | ||||
| ================================= | ||||
| 
 | ||||
| _Version 3, 19 November 2007_ | ||||
| _Copyright (C) 2007 Free Software Foundation, Inc. <<https://fsf.org/>>_ | ||||
| 
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| Everyone is permitted to copy and distribute verbatim copies of this | ||||
| license document, but changing it is not allowed. | ||||
| 
 | ||||
| ## Preamble | ||||
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| "This License" refers to version 3 of the GNU Affero General Public | ||||
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| "Copyright" also means copyright-like laws that apply to other kinds | ||||
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| ### 3. Protecting Users' Legal Rights From Anti-Circumvention Law. | ||||
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| ### 4. Conveying Verbatim Copies. | ||||
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| ### 7. Additional Terms. | ||||
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| "Additional permissions" are terms that supplement the terms of this | ||||
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 | ||||
| ### 8. Termination. | ||||
| 
 | ||||
| You may not propagate or modify a covered work except as expressly | ||||
| provided under this License. Any attempt otherwise to propagate or | ||||
| modify it is void, and will automatically terminate your rights under | ||||
| this License (including any patent licenses granted under the third | ||||
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| 
 | ||||
| However, if you cease all violation of this License, then your license | ||||
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| unless and until the copyright holder explicitly and finally | ||||
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| Moreover, your license from a particular copyright holder is | ||||
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| your receipt of the notice. | ||||
| 
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| Termination of your rights under this section does not terminate the | ||||
| licenses of parties who have received copies or rights from you under | ||||
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| material under section 10. | ||||
| 
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| ### 9. Acceptance Not Required for Having Copies. | ||||
| 
 | ||||
| You are not required to accept this License in order to receive or run | ||||
| a copy of the Program. Ancillary propagation of a covered work | ||||
| occurring solely as a consequence of using peer-to-peer transmission | ||||
| to receive a copy likewise does not require acceptance. However, | ||||
| nothing other than this License grants you permission to propagate or | ||||
| modify any covered work. These actions infringe copyright if you do | ||||
| not accept this License. Therefore, by modifying or propagating a | ||||
| covered work, you indicate your acceptance of this License to do so. | ||||
| 
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| ### 10. Automatic Licensing of Downstream Recipients. | ||||
| 
 | ||||
| Each time you convey a covered work, the recipient automatically | ||||
| receives a license from the original licensors, to run, modify and | ||||
| propagate that work, subject to this License. You are not responsible | ||||
| for enforcing compliance by third parties with this License. | ||||
| 
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| An "entity transaction" is a transaction transferring control of an | ||||
| organization, or substantially all assets of one, or subdividing an | ||||
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| Corresponding Source of the work from the predecessor in interest, if | ||||
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| 
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| You may not impose any further restrictions on the exercise of the | ||||
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| not impose a license fee, royalty, or other charge for exercise of | ||||
| rights granted under this License, and you may not initiate litigation | ||||
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| any patent claim is infringed by making, using, selling, offering for | ||||
| sale, or importing the Program or any portion of it. | ||||
| 
 | ||||
| ### 11. Patents. | ||||
| 
 | ||||
| A "contributor" is a copyright holder who authorizes use under this | ||||
| License of the Program or a work on which the Program is based. The | ||||
| work thus licensed is called the contributor's "contributor version". | ||||
| 
 | ||||
| A contributor's "essential patent claims" are all patent claims owned | ||||
| or controlled by the contributor, whether already acquired or | ||||
| hereafter acquired, that would be infringed by some manner, permitted | ||||
| by this License, of making, using, or selling its contributor version, | ||||
| but do not include claims that would be infringed only as a | ||||
| consequence of further modification of the contributor version. For | ||||
| purposes of this definition, "control" includes the right to grant | ||||
| patent sublicenses in a manner consistent with the requirements of | ||||
| this License. | ||||
| 
 | ||||
| Each contributor grants you a non-exclusive, worldwide, royalty-free | ||||
| patent license under the contributor's essential patent claims, to | ||||
| make, use, sell, offer for sale, import and otherwise run, modify and | ||||
| propagate the contents of its contributor version. | ||||
| 
 | ||||
| In the following three paragraphs, a "patent license" is any express | ||||
| agreement or commitment, however denominated, not to enforce a patent | ||||
| (such as an express permission to practice a patent or covenant not to | ||||
| sue for patent infringement). To "grant" such a patent license to a | ||||
| party means to make such an agreement or commitment not to enforce a | ||||
| patent against the party. | ||||
| 
 | ||||
| If you convey a covered work, knowingly relying on a patent license, | ||||
| and the Corresponding Source of the work is not available for anyone | ||||
| to copy, free of charge and under the terms of this License, through a | ||||
| publicly available network server or other readily accessible means, | ||||
| then you must either (1) cause the Corresponding Source to be so | ||||
| available, or (2) arrange to deprive yourself of the benefit of the | ||||
| patent license for this particular work, or (3) arrange, in a manner | ||||
| consistent with the requirements of this License, to extend the patent | ||||
| license to downstream recipients. "Knowingly relying" means you have | ||||
| actual knowledge that, but for the patent license, your conveying the | ||||
| covered work in a country, or your recipient's use of the covered work | ||||
| in a country, would infringe one or more identifiable patents in that | ||||
| country that you have reason to believe are valid. | ||||
| 
 | ||||
| If, pursuant to or in connection with a single transaction or | ||||
| arrangement, you convey, or propagate by procuring conveyance of, a | ||||
| covered work, and grant a patent license to some of the parties | ||||
| receiving the covered work authorizing them to use, propagate, modify | ||||
| or convey a specific copy of the covered work, then the patent license | ||||
| you grant is automatically extended to all recipients of the covered | ||||
| work and works based on it. | ||||
| 
 | ||||
| A patent license is "discriminatory" if it does not include within the | ||||
| scope of its coverage, prohibits the exercise of, or is conditioned on | ||||
| the non-exercise of one or more of the rights that are specifically | ||||
| granted under this License. You may not convey a covered work if you | ||||
| are a party to an arrangement with a third party that is in the | ||||
| business of distributing software, under which you make payment to the | ||||
| third party based on the extent of your activity of conveying the | ||||
| work, and under which the third party grants, to any of the parties | ||||
| who would receive the covered work from you, a discriminatory patent | ||||
| license (a) in connection with copies of the covered work conveyed by | ||||
| you (or copies made from those copies), or (b) primarily for and in | ||||
| connection with specific products or compilations that contain the | ||||
| covered work, unless you entered into that arrangement, or that patent | ||||
| license was granted, prior to 28 March 2007. | ||||
| 
 | ||||
| Nothing in this License shall be construed as excluding or limiting | ||||
| any implied license or other defenses to infringement that may | ||||
| otherwise be available to you under applicable patent law. | ||||
| 
 | ||||
| ### 12. No Surrender of Others' Freedom. | ||||
| 
 | ||||
| If conditions are imposed on you (whether by court order, agreement or | ||||
| otherwise) that contradict the conditions of this License, they do not | ||||
| excuse you from the conditions of this License. If you cannot convey a | ||||
| covered work so as to satisfy simultaneously your obligations under | ||||
| this License and any other pertinent obligations, then as a | ||||
| consequence you may not convey it at all. For example, if you agree to | ||||
| terms that obligate you to collect a royalty for further conveying | ||||
| from those to whom you convey the Program, the only way you could | ||||
| satisfy both those terms and this License would be to refrain entirely | ||||
| from conveying the Program. | ||||
| 
 | ||||
| ### 13. Remote Network Interaction; Use with the GNU General Public License. | ||||
| 
 | ||||
| Notwithstanding any other provision of this License, if you modify the | ||||
| Program, your modified version must prominently offer all users | ||||
| interacting with it remotely through a computer network (if your | ||||
| version supports such interaction) an opportunity to receive the | ||||
| Corresponding Source of your version by providing access to the | ||||
| Corresponding Source from a network server at no charge, through some | ||||
| standard or customary means of facilitating copying of software. This | ||||
| Corresponding Source shall include the Corresponding Source for any | ||||
| work covered by version 3 of the GNU General Public License that is | ||||
| incorporated pursuant to the following paragraph. | ||||
| 
 | ||||
| Notwithstanding any other provision of this License, you have | ||||
| permission to link or combine any covered work with a work licensed | ||||
| under version 3 of the GNU General Public License into a single | ||||
| combined work, and to convey the resulting work. The terms of this | ||||
| License will continue to apply to the part which is the covered work, | ||||
| but the work with which it is combined will remain governed by version | ||||
| 3 of the GNU General Public License. | ||||
| 
 | ||||
| ### 14. Revised Versions of this License. | ||||
| 
 | ||||
| The Free Software Foundation may publish revised and/or new versions | ||||
| of the GNU Affero General Public License from time to time. Such new | ||||
| versions will be similar in spirit to the present version, but may | ||||
| differ in detail to address new problems or concerns. | ||||
| 
 | ||||
| Each version is given a distinguishing version number. If the Program | ||||
| specifies that a certain numbered version of the GNU Affero General | ||||
| Public License "or any later version" applies to it, you have the | ||||
| option of following the terms and conditions either of that numbered | ||||
| version or of any later version published by the Free Software | ||||
| Foundation. If the Program does not specify a version number of the | ||||
| GNU Affero General Public License, you may choose any version ever | ||||
| published by the Free Software Foundation. | ||||
| 
 | ||||
| If the Program specifies that a proxy can decide which future versions | ||||
| of the GNU Affero General Public License can be used, that proxy's | ||||
| public statement of acceptance of a version permanently authorizes you | ||||
| to choose that version for the Program. | ||||
| 
 | ||||
| Later license versions may give you additional or different | ||||
| permissions. However, no additional obligations are imposed on any | ||||
| author or copyright holder as a result of your choosing to follow a | ||||
| later version. | ||||
| 
 | ||||
| ### 15. Disclaimer of Warranty. | ||||
| 
 | ||||
| THERE IS NO WARRANTY FOR THE PROGRAM, TO THE EXTENT PERMITTED BY | ||||
| APPLICABLE LAW. EXCEPT WHEN OTHERWISE STATED IN WRITING THE COPYRIGHT | ||||
| HOLDERS AND/OR OTHER PARTIES PROVIDE THE PROGRAM "AS IS" WITHOUT | ||||
| WARRANTY OF ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING, BUT NOT | ||||
| LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR | ||||
| A PARTICULAR PURPOSE. THE ENTIRE RISK AS TO THE QUALITY AND | ||||
| PERFORMANCE OF THE PROGRAM IS WITH YOU. SHOULD THE PROGRAM PROVE | ||||
| DEFECTIVE, YOU ASSUME THE COST OF ALL NECESSARY SERVICING, REPAIR OR | ||||
| CORRECTION. | ||||
| 
 | ||||
| ### 16. Limitation of Liability. | ||||
| 
 | ||||
| IN NO EVENT UNLESS REQUIRED BY APPLICABLE LAW OR AGREED TO IN WRITING | ||||
| WILL ANY COPYRIGHT HOLDER, OR ANY OTHER PARTY WHO MODIFIES AND/OR | ||||
| CONVEYS THE PROGRAM AS PERMITTED ABOVE, BE LIABLE TO YOU FOR DAMAGES, | ||||
| INCLUDING ANY GENERAL, SPECIAL, INCIDENTAL OR CONSEQUENTIAL DAMAGES | ||||
| ARISING OUT OF THE USE OR INABILITY TO USE THE PROGRAM (INCLUDING BUT | ||||
| NOT LIMITED TO LOSS OF DATA OR DATA BEING RENDERED INACCURATE OR | ||||
| LOSSES SUSTAINED BY YOU OR THIRD PARTIES OR A FAILURE OF THE PROGRAM | ||||
| TO OPERATE WITH ANY OTHER PROGRAMS), EVEN IF SUCH HOLDER OR OTHER | ||||
| PARTY HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES. | ||||
| 
 | ||||
| ### 17. Interpretation of Sections 15 and 16. | ||||
| 
 | ||||
| If the disclaimer of warranty and limitation of liability provided | ||||
| above cannot be given local legal effect according to their terms, | ||||
| reviewing courts shall apply local law that most closely approximates | ||||
| an absolute waiver of all civil liability in connection with the | ||||
| Program, unless a warranty or assumption of liability accompanies a | ||||
| copy of the Program in return for a fee. | ||||
| 
 | ||||
| END OF TERMS AND CONDITIONS | ||||
| 
 | ||||
| ## How to Apply These Terms to Your New Programs | ||||
| 
 | ||||
| If you develop a new program, and you want it to be of the greatest | ||||
| possible use to the public, the best way to achieve this is to make it | ||||
| free software which everyone can redistribute and change under these | ||||
| terms. | ||||
| 
 | ||||
| To do so, attach the following notices to the program. It is safest to | ||||
| attach them to the start of each source file to most effectively state | ||||
| the exclusion of warranty; and each file should have at least the | ||||
| "copyright" line and a pointer to where the full notice is found. | ||||
| 
 | ||||
|         <one line to give the program's name and a brief idea of what it does.> | ||||
|         Copyright (C) <year>  <name of author> | ||||
| 
 | ||||
|         This program is free software: you can redistribute it and/or modify | ||||
|         it under the terms of the GNU Affero General Public License as | ||||
|         published by the Free Software Foundation, either version 3 of the | ||||
|         License, or (at your option) any later version. | ||||
| 
 | ||||
|         This program is distributed in the hope that it will be useful, | ||||
|         but WITHOUT ANY WARRANTY; without even the implied warranty of | ||||
|         MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the | ||||
|         GNU Affero General Public License for more details. | ||||
| 
 | ||||
|         You should have received a copy of the GNU Affero General Public License | ||||
|         along with this program.  If not, see <https://www.gnu.org/licenses/>. | ||||
| 
 | ||||
| Also add information on how to contact you by electronic and paper | ||||
| mail. | ||||
| 
 | ||||
| If your software can interact with users remotely through a computer | ||||
| network, you should also make sure that it provides a way for users to | ||||
| get its source. For example, if your program is a web application, its | ||||
| interface could display a "Source" link that leads users to an archive | ||||
| of the code. There are many ways you could offer source, and different | ||||
| solutions will be better for different programs; see section 13 for | ||||
| the specific requirements. | ||||
| 
 | ||||
| You should also get your employer (if you work as a programmer) or | ||||
| school, if any, to sign a "copyright disclaimer" for the program, if | ||||
| necessary. For more information on this, and how to apply and follow | ||||
| the GNU AGPL, see <https://www.gnu.org/licenses/>. | ||||
							
								
								
									
										13
									
								
								NAMESPACE
									
										
									
									
									
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										13
									
								
								NAMESPACE
									
										
									
									
									
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							|  | @ -0,0 +1,13 @@ | |||
| # Generated by roxygen2: do not edit by hand | ||||
| 
 | ||||
| export(run_app) | ||||
| import(shiny) | ||||
| importFrom(data.table,":=") | ||||
| importFrom(data.table,.BY) | ||||
| importFrom(data.table,.EACHI) | ||||
| importFrom(data.table,.GRP) | ||||
| importFrom(data.table,.I) | ||||
| importFrom(data.table,.N) | ||||
| importFrom(data.table,.NGRP) | ||||
| importFrom(data.table,.SD) | ||||
| importFrom(data.table,data.table) | ||||
							
								
								
									
										8
									
								
								R/app.R
									
										
									
									
									
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										8
									
								
								R/app.R
									
										
									
									
									
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							|  | @ -0,0 +1,8 @@ | |||
| #' Run the application server. | ||||
| #' | ||||
| #' @param port The port to serve the application on. | ||||
| #' | ||||
| #' @export | ||||
| run_app <- function(port = 3464) { | ||||
|     runApp(shinyApp(ui, server), port = port) | ||||
| } | ||||
							
								
								
									
										2
									
								
								R/data.R
									
										
									
									
									
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										2
									
								
								R/data.R
									
										
									
									
									
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							|  | @ -0,0 +1,2 @@ | |||
| #' A `data.table` containig data on genes and their expression behavior. | ||||
| "genes" | ||||
							
								
								
									
										41
									
								
								R/server.R
									
										
									
									
									
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										41
									
								
								R/server.R
									
										
									
									
									
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							|  | @ -0,0 +1,41 @@ | |||
| #' Server implementing the main user interface. | ||||
| #' @noRd | ||||
| server <- function(input, output) { | ||||
|     output$all_data <- DT::renderDataTable({ | ||||
|         data <- ubigen::genes[, .( | ||||
|             "Gene" = glue::glue_data( | ||||
|                 ubigen::genes, | ||||
|                 "<a href=\"https://www.ensembl.org/Homo_sapiens/Gene/Summary", | ||||
|                 "?db=core;g={gene}\" target=\"_blank\">{hgnc_name}</a>" | ||||
|             ), | ||||
|             "Rank" = rank, | ||||
|             "Score" = score, | ||||
|             "Median" = median_expression, | ||||
|             "Mean" = mean_expression, | ||||
|             "Standard deviation" = sd_expression, | ||||
|             "Expressed" = above_zero, | ||||
|             "Above 50 TPM" = above_threshold, | ||||
|             "Above median" = above_median, | ||||
|             "Above 95%" = above_95 | ||||
|         )] | ||||
| 
 | ||||
|         DT::datatable( | ||||
|             data, | ||||
|             options = list(pageLength = 100), | ||||
|             rownames = FALSE, | ||||
|             escape = FALSE | ||||
|         ) |> | ||||
|             DT::formatPercentage(c( | ||||
|                 "Score", | ||||
|                 "Expressed", | ||||
|                 "Above 50 TPM", | ||||
|                 "Above median", | ||||
|                 "Above 95%" | ||||
|             )) |> | ||||
|             DT::formatRound(c( | ||||
|                 "Median", | ||||
|                 "Mean", | ||||
|                 "Standard deviation" | ||||
|             )) | ||||
|     }) | ||||
| } | ||||
							
								
								
									
										30
									
								
								R/ui.R
									
										
									
									
									
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										30
									
								
								R/ui.R
									
										
									
									
									
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							|  | @ -0,0 +1,30 @@ | |||
| #' Function for creating the main user interface. | ||||
| #' @noRd | ||||
| ui <- function() { | ||||
|     navbarPage( | ||||
|         theme = bslib::bs_theme( | ||||
|             version = 5, | ||||
|             bootswatch = "united", | ||||
|             primary = "#7d19bf" | ||||
|         ), | ||||
|         title = "Ubigen", | ||||
|         tabPanel( | ||||
|             "Explore", | ||||
|             sidebarLayout( | ||||
|                 sidebarPanel( | ||||
|                     width = 3, | ||||
|                 ), | ||||
|                 mainPanel( | ||||
|                     width = 9, | ||||
|                 ) | ||||
|             ) | ||||
|         ), | ||||
|         tabPanel( | ||||
|             title = "Data", | ||||
|             DT::dataTableOutput("all_data") | ||||
|         ), | ||||
|         tabPanel( | ||||
|             title = "Publication" | ||||
|         ) | ||||
|     ) | ||||
| } | ||||
							
								
								
									
										14
									
								
								R/utils.R
									
										
									
									
									
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										14
									
								
								R/utils.R
									
										
									
									
									
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							|  | @ -0,0 +1,14 @@ | |||
| #' Various things that should be imported into the package namespace. | ||||
| #' | ||||
| #' @importFrom data.table := | ||||
| #' @importFrom data.table .BY | ||||
| #' @importFrom data.table .EACHI | ||||
| #' @importFrom data.table .GRP | ||||
| #' @importFrom data.table .I | ||||
| #' @importFrom data.table .N | ||||
| #' @importFrom data.table .NGRP | ||||
| #' @importFrom data.table .SD | ||||
| #' @importFrom data.table data.table | ||||
| #' | ||||
| #' @import shiny | ||||
| NULL | ||||
							
								
								
									
										
											BIN
										
									
								
								data/genes.rda
									
										
									
									
									
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											BIN
										
									
								
								data/genes.rda
									
										
									
									
									
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										16
									
								
								man/genes.Rd
									
										
									
									
									
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										16
									
								
								man/genes.Rd
									
										
									
									
									
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							|  | @ -0,0 +1,16 @@ | |||
| % Generated by roxygen2: do not edit by hand | ||||
| % Please edit documentation in R/data.R | ||||
| \docType{data} | ||||
| \name{genes} | ||||
| \alias{genes} | ||||
| \title{A \code{data.table} containig data on genes and their expression behavior.} | ||||
| \format{ | ||||
| An object of class \code{data.table} (inherits from \code{data.frame}) with 56156 rows and 13 columns. | ||||
| } | ||||
| \usage{ | ||||
| genes | ||||
| } | ||||
| \description{ | ||||
| A \code{data.table} containig data on genes and their expression behavior. | ||||
| } | ||||
| \keyword{datasets} | ||||
							
								
								
									
										14
									
								
								man/run_app.Rd
									
										
									
									
									
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										14
									
								
								man/run_app.Rd
									
										
									
									
									
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							|  | @ -0,0 +1,14 @@ | |||
| % Generated by roxygen2: do not edit by hand | ||||
| % Please edit documentation in R/app.R | ||||
| \name{run_app} | ||||
| \alias{run_app} | ||||
| \title{Run the application server.} | ||||
| \usage{ | ||||
| run_app(port = 3464) | ||||
| } | ||||
| \arguments{ | ||||
| \item{port}{The port to serve the application on.} | ||||
| } | ||||
| \description{ | ||||
| Run the application server. | ||||
| } | ||||
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