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gsea: Move to separate module
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parent
045d4dd6ad
commit
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2 changed files with 88 additions and 66 deletions
68
R/results.R
68
R/results.R
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@ -152,11 +152,7 @@ results_ui <- function(id, options) {
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title = "g:Profiler",
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div(
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style = "margin-top: 16px",
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plotly::plotlyOutput("gost_plot"),
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),
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div(
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style = "margin-top: 16px",
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DT::DTOutput(NS(id, "gost_details"))
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gsea_ui(NS(id, "gsea"))
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)
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)
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)
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@ -407,67 +403,7 @@ results_server <- function(id, options, analysis) {
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)
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})
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gost <- reactive({
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withProgress(
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message = "Querying g:Profiler",
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value = 0.0,
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{ # nolint
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setProgress(0.2)
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gprofiler2::gost(
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results_filtered()[, gene],
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custom_bg = preset()$gene_ids,
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domain_scope = "custom_annotated"
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)
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}
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)
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}) |> bindCache(results_filtered(), preset())
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output$gost_plot <- plotly::renderPlotly({
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gprofiler2::gostplot(
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gost(),
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capped = FALSE,
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interactive = TRUE
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)
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})
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output$gost_details <- DT::renderDT({
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data <- data.table(gost()$result)
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setorder(data, p_value)
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data[, total_ratio := term_size / effective_domain_size]
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data[, query_ratio := intersection_size / query_size]
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data[, increase := (query_ratio - total_ratio) / total_ratio]
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data <- data[, .(
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source,
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term_name,
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total_ratio,
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query_ratio,
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increase,
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p_value
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)]
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dt <- DT::datatable(
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data,
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rownames = FALSE,
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colnames = c(
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"Source",
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"Term",
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"Total ratio",
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"Query ratio",
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"Increase",
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"p-value"
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),
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options = list(
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pageLength = 25
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)
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) |>
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DT::formatRound("p_value", digits = 4) |>
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DT::formatPercentage(
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c("total_ratio", "query_ratio", "increase"),
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digits = 2
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)
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})
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gsea_server("gsea", results_filtered)
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})
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}
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