| 
									
										
										
										
											2021-10-20 15:34:52 +02:00
										 |  |  | # Species IDs of known replicatively aging species. | 
					
						
							| 
									
										
										
										
											2021-10-19 14:15:28 +02:00
										 |  |  | species_ids_replicative <- c( | 
					
						
							|  |  |  |     "bihybrid", | 
					
						
							|  |  |  |     "btaurus", | 
					
						
							|  |  |  |     "bthybrid", | 
					
						
							|  |  |  |     "cfamiliaris", | 
					
						
							|  |  |  |     "chircus", | 
					
						
							|  |  |  |     "cjacchus", | 
					
						
							|  |  |  |     "clfamiliaris", | 
					
						
							|  |  |  |     "csabaeus", | 
					
						
							|  |  |  |     "ecaballus", | 
					
						
							|  |  |  |     "fcatus", | 
					
						
							|  |  |  |     "ggorilla", | 
					
						
							|  |  |  |     "hsapiens", | 
					
						
							|  |  |  |     "lafricana", | 
					
						
							|  |  |  |     "mfascicularis", | 
					
						
							|  |  |  |     "mmulatta", | 
					
						
							|  |  |  |     "mmurinus", | 
					
						
							|  |  |  |     "mnemestrina", | 
					
						
							|  |  |  |     "nleucogenys", | 
					
						
							|  |  |  |     "oaries", | 
					
						
							|  |  |  |     "pabelii", | 
					
						
							|  |  |  |     "panubis", | 
					
						
							|  |  |  |     "ppaniscus", | 
					
						
							|  |  |  |     "ptroglodytes", | 
					
						
							|  |  |  |     "sscrofa", | 
					
						
							|  |  |  |     "tgelada" | 
					
						
							|  |  |  | ) | 
					
						
							|  |  |  | 
 | 
					
						
							| 
									
										
										
										
											2021-10-20 15:34:52 +02:00
										 |  |  | # Gene names of genes for verified TPE-OLD genes. | 
					
						
							| 
									
										
										
										
											2021-10-19 14:15:28 +02:00
										 |  |  | genes_verified_tpe_old <- c( | 
					
						
							|  |  |  |     "C1S", | 
					
						
							|  |  |  |     "DSP", | 
					
						
							|  |  |  |     "ISG15", | 
					
						
							|  |  |  |     "SORBS2", | 
					
						
							|  |  |  |     "TERT" | 
					
						
							|  |  |  | ) | 
					
						
							|  |  |  | 
 | 
					
						
							| 
									
										
										
										
											2021-10-20 15:34:52 +02:00
										 |  |  | # Gene names of genes with a suggested TPE-OLD. | 
					
						
							| 
									
										
										
										
											2021-10-19 14:15:28 +02:00
										 |  |  | genes_suggested_tpe_old <- c( | 
					
						
							|  |  |  |     "AKAP3", | 
					
						
							|  |  |  |     "ANO2", | 
					
						
							|  |  |  |     "CCND2", | 
					
						
							|  |  |  |     "CD163L1", | 
					
						
							|  |  |  |     "CD9", | 
					
						
							|  |  |  |     "FOXM1", | 
					
						
							|  |  |  |     "GALNT8", | 
					
						
							|  |  |  |     "NDUFA9", | 
					
						
							|  |  |  |     "TEAD4", | 
					
						
							|  |  |  |     "TIGAR", | 
					
						
							|  |  |  |     "TSPAN9" | 
					
						
							|  |  |  | ) | 
					
						
							|  |  |  | 
 | 
					
						
							| 
									
										
										
										
											2021-10-20 15:34:52 +02:00
										 |  |  | # Genes from [geposan] and their TPE-OLD status. | 
					
						
							| 
									
										
										
										
											2021-10-19 14:15:28 +02:00
										 |  |  | genes <- geposan::genes[, .( | 
					
						
							|  |  |  |     id, | 
					
						
							|  |  |  |     name, | 
					
						
							|  |  |  |     chromosome, | 
					
						
							|  |  |  |     suggested = name %chin% genes_suggested_tpe_old, | 
					
						
							|  |  |  |     verified = name %chin% genes_verified_tpe_old | 
					
						
							|  |  |  | )] | 
					
						
							|  |  |  | 
 | 
					
						
							| 
									
										
										
										
											2021-10-20 15:34:52 +02:00
										 |  |  | # All available methods from [geposan] and additional information on them. | 
					
						
							| 
									
										
										
										
											2021-12-16 13:52:14 +01:00
										 |  |  | methods <- geposan::all_methods() | 
					
						
							| 
									
										
										
										
											2021-10-19 14:15:28 +02:00
										 |  |  | 
 | 
					
						
							| 
									
										
										
										
											2021-11-14 22:34:46 +01:00
										 |  |  | # IDs of methods for geposan. | 
					
						
							|  |  |  | method_ids <- sapply(methods, function(method) method$id) | 
					
						
							|  |  |  | 
 | 
					
						
							|  |  |  | # Names of methods for geposan. | 
					
						
							|  |  |  | method_names <- sapply(methods, function(method) method$name) |