# Score the mean distance of genes to the telomeres across species. # # A score will be given to each gene such that 0.0 corresponds to the maximal # mean distance across all genes and 1.0 corresponds to a distance of 0. proximity <- function(distances, preset, progress = NULL) { # Prefilter distances by species and gene. distances <- distances[ species %chin% preset$species_ids & gene %chin% preset$gene_ids ] # Compute the score as described above. distances <- distances[, .(mean_distance = mean(distance)), by = "gene"] max_distance <- distances[, max(mean_distance)] distances[, score := 1 - mean_distance / max_distance] if (!is.null(progress)) { # We do everything in one go, so it's not possible to report detailed # progress information. As the method is relatively quick, this should # not be a problem. progress(1.0) } distances[, .(gene, score)] }