proximity: Use median distance by default

This commit is contained in:
Elias Projahn 2022-02-24 17:44:04 +01:00
parent 99bc6794b9
commit 2fb48be0e3
2 changed files with 25 additions and 11 deletions

48
R/method_proximity.R Normal file
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#' Score the distance of genes to the telomeres across species.
#'
#' A score will be given to each gene such that 0.0 corresponds to the maximal
#' distance across all genes and 1.0 corresponds to a distance of 0.
#'
#' @param summarize A function for combining the different proximities into one
#' metric. By default, [stats::median()] is used. Other suggested options
#' include [min()] and [mean()].
#'
#' @return An object of class `geposan_method`.
#'
#' @export
proximity <- function(summarize = stats::median) {
method(
id = "proximity",
name = "Proximity",
description = "Proximity to telomeres",
function(preset, progress) {
species_ids <- preset$species_ids
gene_ids <- preset$gene_ids
cached("proximity", c(species_ids, gene_ids), {
# Prefilter distances by species and gene.
data <- geposan::distances[
species %chin% preset$species_ids &
gene %chin% preset$gene_ids
]
# Compute the score as described above.
data <- data[,
.(combined_distance = as.double(summarize(distance))),
by = "gene"
]
# Normalize scores.
data[, score := 1 - combined_distance / max(combined_distance)]
progress(1.0)
result(
method = "proximity",
scores = data[, .(gene, score)],
details = list(data = data)
)
})
}
)
}